Wednesday, March 27, 2013

Scientist / Sr. Scientist


Scientist / Sr. Scientist
Locations Chennai
Experience 4 - 6 years
Education Phd
Job Ref code GLS-SCT
Responsibilities
  • Conduct analyses on Next-Gen sequencing data including data derived in ChIP-Seq, RNA-Seq, miRNA-Seq and other experimental models to a customer base including leading pharmaceutical, biotech and academic institutions worldwide.
  • Define and implement quality control procedures at both technological and biological levels to ensure quality of extreme high volume of next-generation sequencing data.
  • Develop cutting-edge algorithms, pipelines, and applications to analyze data from our external customers, e.g. next generation sequencing data. He or she will work hand-in-hand with our software development team to serve as domain expert with in the team
  • Develop and apply algorithms and statistical models to analyze and interpret next-generation sequencing data.  Implement robust and automated pipelines and tools to support large scale bioinformatics analysis.
  • Conduct analysis and interpretation on data from genomic platforms including expression, exon, tiling, promoter and others primary, secondary and tertiary data analysis as per clients requirement
  • Conduct data analysis and interpretation on other large data types in genomic context.
  • Perform hands-on tasks as well as supervise a team of bioinformatics and biologists
  • Develop bioinformatics analysis processes in collaboration with colleagues within the lab as well as with the multidisciplinary teams.
  • Manage work flows including experimental design, analyses of data quality, genome and meta-genome integration and others
  • Write utility scripts, macros and/or custom programs or algorithms in support of biological discovery
  • Coordinate with biologists and/or other bioinformaticians in the design of models summarizing/explaining experimental data; provide interpretive analyses of data derived from different experimental platforms to generate biological meaningful data set
  • Prepare reports and publication quality graphics summarizing experimental data including providing written documents to the clients.
  • Proactively monitor technological developments and new genomic applications.
  • Responsible for ensuring efficient budget administration and for reporting activities of the Unit.
Desired Experience and Knowledge
  • Minimum of two (2) years of post-graduation experience in the field of bioinformatics and/or functional genomics
  • A broad familiarity working in a high performance computing environment
  • Demonstrated programming expertise in one or more object-oriented languages such as Java/C++ or equivalent
  • Demonstrated familiarity working with statistical/mathematical packages such as R/MATLAB or equivalent
  • Demonstrated experience working with large biological data
  • Demonstrated fluency working with Windows, Macintosh and/or UNIX/Linux environment
  • Proven programming experience in a scripting language such as Perl or Python
  • A working understanding of basic statistics used for biological data analyses and the ability to relate those findings to biologists
  • Demonstrated experience extracting and describing complex high dimensional data and presenting those data in a biologically meaningful context
  • Strong Publication record
  • Experience in NGS software analysis packages
  • Background MBBS/B Tech(Premier institutes), PhD( Bioinformatics/computational Biology) plus 1-2 years Post Doc exp will be preferable
Skills
  • Flexible and willing to work across multiple projects and technology in a rapidly evolving scientific context.
  • Excellent communication skills in English and organizational skills.
  • Self-starter and proactive.
  • Highly motivated, career-oriented and hard-working
  • Strong analytical and troubleshooting skills and ability to innovate.
  • Previous managerial experience is a strong plus
  • Interested to work with a multi-disciplinary team combining genomics and computational approaches with experimental biology
About Company Genome Life Sciences (GLS) is the India R&D centre of Genome International Corporation and is one of the handful of companies having in-house R&D recognition from DSIR-Ministry of Science and Technology. Genome Life Sciences (GLS) was established in 2004 with the vision of developing innovative Bioinformatics algorithms, tools, and databases for biomarker discovery in the areas of healthcare, veterinary, agriculture, food and related industries.
The company provides life science databases of unique content developed with data mining algorithms along with their interactive and dynamic user interfaces. In addition, it provides data analysis products/services for the analysis of Next Generation Sequencing (NGS) data generated from all major platforms such as Illumina GA/HiSeq, ABI SOLiD, and Roche 454. For more details please visit our website: www.genome.com  and www.genomels.com  

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